Careful, Grapefruit-Drug Interactions Can Cause Deadly Effects!

One of the most popular fruit among lovers of healthy food, but also among those who want to lose weight, it is certainly – grapefruit.

The fruit, however, is the real king of contradictories. On the one side it improves immunity and melts pounds/fats, on the other side it can have deadly effects, but only if combined with some medicines.

Grapefruit contains only 42 calories per 100 grams and 33 milligrams of vitamin C. In addition, it contains some compounds that have a positive impact on fat loss and brings us, also, 12 milligrams of calcium and 148 milligrams of potassium.

Unfortunately, along with the almost magical properties that it has, grapefruit can be very dangerous. Namely, it contains certain substances which in combination with some medicines can alter metabolism in the body.

This “grapefruit effect” was unveiled more than 20 years ago, and every year the list of drugs that should not be combined with the juice grows bigger. More than 40 drugs have so far made it to this list, among which there are some medicines used for cancer cure/prevention, high blood pressure, as well as some analgesics.

The consequences can be various – from the worst, sudden death, followed by gastrointestinal bleeding, kidney failure and breathing problems. Scientist say the adverse effects of this juice can be seen immediately even if only one glass of this juice is drunk after those medicines are taken.

Advice: If a doctor prescribes a drug, and you drink or eat grapefruit, be sure to notify him, so he can tell you whether the drug can or cannot be combined with the juice.

Here is the list of medicines that can cause deadly effects if used with grapefruit:

  • Anti-cancer drugs: Crizotinib, Dasatinib, Erlotinib, Everolimus, Lapatinib, Nilotinib, Pazopanib, Sunitinib, Vandetanib, Venurafenib.
  • Anti-infection drugs: Erythromycin, Halofantrine, Maraviroc, Primaquine, Quinine, Rilpivirine
  • Anti-lipemic drugs: Atorvastatin, Lovastatin, Simvastatin
  • Cardiovascular drugs: Amiodarone, Apixaban, Clopidogrel, Dronedarone, Eplerenone, Felodipine, Nifedipine, Quinidine, Rivaroxaban, Ticagrelor
  • CNS drugs: Alfentanil (oral), Buspirone, Dextromethorphan, Fentanyl (oral), Ketamine (oral), Lurasidone, Oxycodone, Pimozide, Quetiapine, Triazolam, Ziprasidone
  • Gastrointestinal drugs: Domperidone
  • Immunosuppressants: Cyclosporine, Everolimus, Sirolimus, Tacrolimus
  • Urinary tract drugs: Darifenacin, Fesoterodine, Solifenacin, Silodosin, Tamsulosin


Source: Ibtimes


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